Hello iris, im sorry to hear of your husbands diagnosis. There is prooved connection between this malignant tumor and primary sclerosis cholangitis autoimmune disease and parasitic infection in biliary ducts clonorchis sinensis and opisthorchis viverrini, both in southeast asia. Cholangiocarcinomas cccs are malignancies of the biliary duct system perihilar tumors, also called klatskin tumors after klatskins description of them in the etiology. Cholangiocarcinoma is an aggressive form of cancer and commonly diagnosed. Klatskin was among the first to link the australia antigen to hepatitis b, to relate acute liver injury to prognosis, and to recognize that alcoholic hyperlipidemia could give rise to pancreatitis. Klatskin tumor is a type of cancerous growth develops at the junction between right and left biliary duct from where main bile duct is formed. Siegel r, ma j, zou z, et al cancer statistics, 2014. It is most frequently found in the confluence of the hepatic ducts, where it is called hilar cholangiocarcinoma or klatskin tumor.
Demographics, tumor characteristics, treatment, and survival. In 1965 he described the unique features of cholangiocarcinoma at the bifurcation of the main intrahepatic bile ducts, which came to be called the. Javier alejandro comas garcia hospital clinico quirurgico arnaldo milian castro, santa clara, villa clara. Oct 15, 2005 this all happened during a three week period. One finally did an ercp which showed john had a tumor in the bile ducts, where they came together into one. Our study provides the most recent comprehensive information on klatskin tumors from the seer cancer registry. Klatskin tumor article about klatskin tumor by the free. Cancer is cancer no matter were in the body it is found, there are deffinately more desirable places to find it if we could choose. Learn about the risk factors for bile duct cancer and what you might be able to do to help lower your risk.
She had liver resection surgery in jan 2006 and has is cancer free today. Klatskin tumor genetic and rare diseases information center. Oct, 2016 klatskin tumors are are a type of cholangiocarcinoma that begins in an area called the hilum, where the left and right bile ducts join and leave the liver. Request pdf hilar cholangiocarcinoma klatskin tumor this is a clinical case of a 71yearold man with an obstructive lesion of the hepatic hilum, the clinical, imaging studies and the lab. Nomograms predict survival outcome of klatskin tumors. Klatskin tumor genetic and rare diseases information. Among this almost 60% to 70 % biliary duct cancer is klatskin tumor 1,2. All klatskin tumor messages empowering cancer patients to. Klatskin tumors are are a type of cholangiocarcinoma that begins in an area called the hilum, where the left and right bile ducts join and leave the liver. Only malignant and microscopically confirmed cases were included. It occurs at the confluence of the right and left hepatic bile duct. Comprometimento linfonodal perihilar hepatico e do retroperitonio no estadiamento. Get an overview of bile duct cancer and the latest key statistics in the us.
Early detection and diagnosis were associated with a higher rate of os in klatskin tumor patients. Diagnosis, preoperative evaluation and surgical considerations. My wife dawn was diagnosed with a klatskins tumor in december of 2005. A klatskin tumor or hilar cholangiocarcinoma is a cholangiocarcinoma cancer of the biliary tree occurring at the confluence of the right and left hepatic bile ducts. Cholangiocarcinomas cccs are malignancies of the biliary duct system perihilar tumors, also called klatskin tumors after klatskin s description of them in the etiology. The icdo3 histological code used for klatskin tumors was 81623. The disease was named after gerald klatskin, who in 1965 described 15 cases and found some characteristics for this type of cholangiocarcinoma. Hilar cholangiocarcinoma klatskin tumor request pdf. Demographics, tumor characteristics, treatment, and.
Nomograms predict survival outcome of klatskin tumors patients. Hulda clarks parasite cleanse, cancer needs to be reversed out of your body. Mark fraiman on december 11, 2015 in bile cancer, bile duct cancer, bile duct disease each year approximately 15,000 new cases of liver and biliary tract cancers are diagnosed in the united states. Feb 08, 2018 the topographical codes used for klatskin tumors were. Dec 11, 2015 a closer look at klatskin tumor treatment options by dr. About 5% to 10% of bile duct cancers are intrahepatic. Conclusions the klatskin tumor group had poorer rates of os and cancerspecific survival than the icca and hcc groups. Klatskin tumor is a term that was traditionally given to a hilar cholangiocarcinoma, occurring at the bifurcation of the common hepatic duct. When they told me john had a cancer called cholangiocarcinoma, i was in shock. Klatskin tumour is a type of cholangiocarcinoma or a tumour of the bile duct system. Mark fraiman, md st joseph medical center liver and pancreas center 23,239 views. Klatskin tumor is quite rare, more in male sex in age 60 years. The seer database was used for this analysis as it is an extensive data center for cancer incidence, staging, treatment, and survival derived from populationbased cancer registries of the united states. Magnetic resonance cholangiopancreaticography showed a dilated intrahepatic bile duct, but did not show the con fluence of the hepatic ducts or the proximal.
American joint committee on cancer ajcc 2004 staging was available for the majority of cases and this was used. Metastasisassociated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients andri lederer,1,2 pia herrmann,1 daniel seehofer,2 manfred dietel,3 johann pratschke,2 peter schlag,4 and ulrike stein1,5 curative treatment of intrahepatic cholangiocarcinoma icc and hilar cholangiocarcinoma. This neoplasia, which originates in the epithelium of the biliary ducts, or cholangiocarcinoma cc, represents 10% of hepatobiliary tumours and 2% of malignant tumours. Cholangiocarcinomas cccs are malignancies of the biliary duct system perihilar tumors, also called klatskin tumors after klatskin s description of them in the etiology of most bile duct cancers remains undetermined.
The prognostic and protective factors were included in the nomogram cindex for survival 0. Diagnostico, evaluacion preoperatoria y consideraciones quirurgicas. Cholangiocarcinoma is a malignant neoplasm of the hepatic bile duct. Perihilar tumors, also called klatskin tumors after klatskin s description of them in 1965, occur at the bifurcation of right and left hepatic ducts. All types of cancerous growth in the biliary duct are termed as cholangiocarcinoma. Distal extrahepatic tumors are located from the upper border of the pancreas to the ampulla. Klatskin tumor is a rare tumor and nonspecific clinical. A tumor that starts in this area is also sometimes called a klatskins tumor. Lorraine days tape cancer doesnt scare me anymore and start on dr.
1261 65 926 38 99 965 32 1517 1522 1444 1573 487 998 1152 1373 754 160 1147 853 1064 1210 1438 303 37 355 225 1029 964 1428 123